References
1. Bickerton, G.R., et al. (2012) Quantifying the chemical beauty of drugs. Nat. Chem., 4, 90-98.
2. Brenk, R., et al. (2007) Lessons learnt from assembling screening libraries for drug discovery for neglected diseases. ChemMedChem, 3, 435-444.
3. Ghose, A.K., Viswanadhan, V.N. and Wendoloski, J.J. (1999) A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases. J. Com. Chem., 1, 55-68.
4. Kerns, E. and Di, L. (2008) Drug-like properties: concepts, structure design and methods: from ADME to toxicity optimization. Academic Press.
5. Lipinski, C.A., et al. (1997) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Delivery Rev., 23, 3-25.
6. Oprea, T.I. (2000) Property distribution of drug-related chemical databases*. J. Comput-Aided. Mol. Des., 14, 251-264.
7. Steinbeck, C., et al. (2003) The Chemistry Development Kit (CDK): An open-source Java library for chemo-and bioinformatics. J. Chem. Inf. Comput. Sci., 43, 493-500.
8. Veber, D.F., et al. (2002) Molecular properties that influence the oral bioavailability of drug candidates. J. Med. Chem., 45, 2615-2623.
9 Yusof, I. and Segall, M.D. (2013) Considering the impact drug-like properties have on the chance of success. Drug Discov. Today, 'in press'.
1. Bickerton, G.R., et al. (2012) Quantifying the chemical beauty of drugs. Nat. Chem., 4, 90-98.
2. Brenk, R., et al. (2007) Lessons learnt from assembling screening libraries for drug discovery for neglected diseases. ChemMedChem, 3, 435-444.
3. Ghose, A.K., Viswanadhan, V.N. and Wendoloski, J.J. (1999) A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases. J. Com. Chem., 1, 55-68.
4. Kerns, E. and Di, L. (2008) Drug-like properties: concepts, structure design and methods: from ADME to toxicity optimization. Academic Press.
5. Lipinski, C.A., et al. (1997) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Delivery Rev., 23, 3-25.
6. Oprea, T.I. (2000) Property distribution of drug-related chemical databases*. J. Comput-Aided. Mol. Des., 14, 251-264.
7. Steinbeck, C., et al. (2003) The Chemistry Development Kit (CDK): An open-source Java library for chemo-and bioinformatics. J. Chem. Inf. Comput. Sci., 43, 493-500.
8. Veber, D.F., et al. (2002) Molecular properties that influence the oral bioavailability of drug candidates. J. Med. Chem., 45, 2615-2623.
9 Yusof, I. and Segall, M.D. (2013) Considering the impact drug-like properties have on the chance of success. Drug Discov. Today, 'in press'.
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